Dermoscopic Follow-up Of Cutaneous Rosai-dorfman: Spontaneous Regression
Hu, C., Cao, Y., Yang, X., Cao, Z., Xu, M., Shi, L., & Wang, X. (2021). Dermoscopic follow-up of cutaneous rosai-dorfman: Spontaneous regression. Photodiagnosis and photodynamic therapy, 34, 102263. https://doi.org/10.1016/j.pdpdt.2021.102263
View Original Source →Abstract
BACKGROUND: Cutaneous rosai-dorfman(CRDD) is a rare non-langerhans cell histiocytosis with unknown origin. Studies reporting the dermoscopic features of CRDD are limited. CASE PRESENTATION: We report a case of a 62-year-old Asian woman with 1-month history of a solitary reddish nodule on her left nose wing which was histolocically diagnosed as CRDD. The lesion underwent spontaneous remission without any intervention.Dermoscopy was utilized for follow-up observation. RESULTS: The dermoscopic features of the CRDD lesion included red-brownish and red-orange background, yellowish follicular keratotic plugs, whitish opaque cotton structures and linear- irregular vessels. These features gradully faded away along with the remission of the lesion. CONCLUSIONS: We describe the dynamic dermoscopic changes of the remission process of CRDD. Dermoscopy is potentially useful in the assessment and follow-up of CRDD patients.
Case Details
Disease Location
Skin
Personal Characteristics
62-year-old woman
Clinical Characteristics
Presented with a red nodule on the left wing of her nose for 1 month with little pain. Physical examination revealed a red exophytic nodule measuring 1.7 × 1.6 cm located on the left nasal wing. Surgical biopsy specimen with diameter of 5 mm was taken and histopathologic study demonstrated a dense dermal infiltrate of large histiocytes, admixed with inflammatory cells composed predominantly of lymphocytes and plasma cells. Areas of emperipolesis were noted. Cutaneous rosai-dorfman disease (crdd) was diagnosed.
Remission Characteristics
On the 4th week follow-up visit, the nodule on her left nose almost disappeared and the characteristic dermoscopic patterns, including yellowish follicular plugs and white cotton materials with linear- irregular vessels, were gone.
Treatment & Mechanisms
Clinical Treatment
Surgical excision