Spontaneous Regression Of A Keratoacanthoma Centrifugum Marginatum
Kim, Y., Helm, K. F., Billingsley, E. M., & Lam, C. (2019). Spontaneous Regression of a Keratoacanthoma Centrifugum Marginatum. Dermatology practical & conceptual, 9(2), 157–159. https://doi.org/10.5826/dpc.0902a16
View Original Source →Abstract
Citation: Kim Y, Helm KF, Billingsley EM, Lam C. Spontaneous regression of a keratoacanthoma centrifugum marginatum. Dermatol Pract Concept. 2019;9(2):157-159. DOI: https://doi.org/10.5826/dpc.0902a16
Case Details
Disease Location
Skin
Personal Characteristics
Caucasian man in his 70s
Clinical Characteristics
Presented with a 3-month history of a large asymptomatic lesion of his left arm. He reported that it initially started as a pinpoint lesion but rapidly grew and stabilized. Initial biopsy gave the diagnosis of moderately differentiated squamous cell carcinoma. Physical examination revealed a 6 × 6 cm, nontender, malodorous plaque with a heaped-up friable tissue rim with clinically normal skin in the center. Second biopsy for histopathological analysis was performed, showing epithelial fragments and fibrosis, consistent with the diagnosis of a central portion of a keratoacanthoma centrifugum marginatum (kcm)
Remission Characteristics
The patient subsequently noticed flattening and reduction in size of the lesion. Three months after initial presentation, physical examination showed a 4 × 5 cm, nontender, nonmalodorous thin plaque with a minor amount of friable tissue and clinically normal skin in the center. A third biopsy was consistent with a regressing kcm
Treatment & Mechanisms
Clinical Treatment
Biopsy x3