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Spontaneous Regression Of A Recalcitrant Wart After Bivalent Papillomavirus Vaccination

Martin, J. M., Mateo, E., & Ramón, D. (2018). Spontaneous Regression of a Recalcitrant Wart after Bivalent Papillomavirus Vaccination. The Journal of pediatrics, 194, 259–259.e1. https://doi.org/10.1016/j.jpeds.2017.11.022

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Case Details

Disease Location

Skin

Personal Characteristics

10-year-old girl

Clinical Characteristics

Presented with a wart located on the right finger of her hand that had appeared 9 months before. It had been refractory to multiple topical treatments used, including cryotherapy (6 sessions), salicylic acid, and cantharidin

Remission Characteristics

Ten days after receiving the first dose of the human papillomavirus (hpv) bivalent vaccine, total remission of the wart was noted

Treatment & Mechanisms

Proposed Remission Mechanisms

In addition to an immune response to the l1 capsid protein, a nonspecific effect related to locally released chemokines could also be involved

Clinical Treatment

Human papillomavirus bivalent vaccine

Non-Clinical Treatment

None reported