Spontaneous Regression Of Carcinoma Of The Stomach.
Sharma DN, Mohanti BK, Shukla NK, Rath GK. spontaneous regression of carcinoma of the stomach. Clin Oncol (R Coll Radiol). 2000;12(5):335-6. PMID: 11315723.
View Original Source →Abstract
An 85-yr-old female was subjected to subtotal gastrectomy for double early carcinomas. Five years later a hemispheric protuberant lesion was observed endoscopically in the residual stomach and found by biopsy to be adenocarcinoma. Because of her poor general condition, anticancerous drugs were not given. She gradually became debilitated, and died 10 months later. At autopsy there was no protuberant lesion in the residual stomach and no cancer was found on multiple-step microscopical sections. A small pancreatic cancer with regional lymph node metastasis was found incidentally. In an immunohistological examination, only the carcinoma of the pancreas and its lymph node metastasis were positively stained with monoclonal anti-CA19-9 antibody-PAP. This is a rare case of a spontaneous regression of human gastric carcinoma, and was proved by autopsy.
Case Details
Disease Location
Stomach
Personal Characteristics
64-year-old male
Clinical Characteristics
Complaints of epigastric pain and repeated episodes of haematemesis of 1- months duration, endoscopy demonstrated an extensive ulceroproliferative growth in the stomach. On exploratory laparotomy a biopsy was taken. Histopathological examination revealed tumour cells consistent with adenocarcinoma. After 1 year, the patient reported to our clinic with minor dyspeptic symptoms
Remission Characteristics
Upper gastrointestinal endoscopy revealed complete regression of the tumour
Treatment & Mechanisms
Proposed Remission Mechanisms
Immunology- cal resistance to tumour growth
Clinical Treatment
Laparotomy