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About the Project

Spontaneous Regression Of Metastatic Squamous Cell Lung Cancer

Ariza-Prota, M. 2018Lung cancer

Ariza-Prota, M., Martínez, C., & Casan, P. (2018). Spontaneous regression of metastatic squamous cell lung cancer. Clinical case reports, 6(6), 995–998. https://doi.org/10.1002/ccr3.1502

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Abstract

Spontaneous regression (SR) of cancer is a rare but confirmed spectacular phenomenon, and it is even rarer in the context of advanced NSCLC. It is essential to understand this phenomenon in order to elucidate the nature of neoplastic disease and develop new treatment methods.

Case Details

Disease Location

Lung, lymph nodes

Personal Characteristics

82-year-old man. Pack-a-day smoker for 45 years and had a history of type ii diabetes treated with medication

Clinical Characteristics

Referred for an evaluation of an abnormal shadow on his chest x-ray. Physical examination showed palpable bilateral cervical lymph nodes and cutaneous nodules on his abdomen, arms, neck, and lip. Chest radiography showed an alveolar infiltrate in the right lower lobe, and the CT scan revealed a round mass in the right lower lobe multiple nodules in the chest wall (12 9 18 mm nodule in the right pectoral muscle and 6 mm nodule in the intercostal muscles between the sixth and seventh left ribs and cervical necrotic lymph nodes. Percutaneous aspiration cytology of the tumor on the left side of the neck (cervical lymph node) and CT-guided needle biopsy of the right lower lobe mass established the diagnosis of squamous lung cell carcinoma with metastases to the cer- vical lymph nodes.

Remission Characteristics

At follow-up, 3 months after the diagnosis, chest radiography and CT scan showed that the primary tumor had decreased in size, and that metastatic cutaneous lesions

Treatment & Mechanisms

Clinical Treatment

Biopsy