Large Lung Mass Lesion With Spontaneous Regression In A Patient With Igg4-related Lung Disease
Iwasaki, K., Araya, T., Kita, T., & Sakai, T. (2022). Large lung mass lesion with spontaneous regression in a patient with IgG4-related lung disease. Respirology case reports, 11(1), e01075. https://doi.org/10.1002/rcr2.1075
View Original Source →Abstract
IgG4-related lung disease (IgG4-RLD) may present with a variety of radiological findings, but large lung mass lesion are rare. Although steroid therapy is strongly recommended for IgG4-RLD with or without symptoms, respirologists should be aware that some patients may not need steroid therapy.
Case Details
Disease Location
Lung
Personal Characteristics
74-year-old man. History of igg4-related pancreatic lesion spontaneously regressing within a month, 6 years ago.
Clinical Characteristics
Suspected lung cancer. PET/CT revealed a strong 18f-fdg accumulation in the lung mass lesion margin. Laboratory tests showed elevated serum igg4 levels. Biopsy samples from the right upper lung mass showed lymphocyte infiltration, obliterative phlebitis and numerous igg4-positive plasma cells. Igg4-related lung disease was diagnosed.
Remission Characteristics
Post diagnosis, the large lung mass shrunk. Four months later, the lesion nearly disappeared
Treatment & Mechanisms
Clinical Treatment
Biopsy