An Elderly Man With A Gingival Mass That Spontaneously Regressed
Gonzalez-Perez, L. M., & Borrero-MARTin, J. J. (2016). An elderly man with a gingival mass that spontaneously regressed. Oral surgery, oral medicine, oral pathology and oral radiology, 121(4), 348–352. https://doi.org/10.1016/j.oooo.2015.08.014
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Disease Location
Left mandible
Personal Characteristics
75-year-old male with arterial hypertension, type 2 diabetes, grade iii hydroureteronephrosis of the right kidney, and degenerative joint disease with severe back pain and limited movement of affected joints (shoulders and hips). He was an occasional tobacco smoker and a social drinker
Clinical Characteristics
2- months history of a painless lesion in the oral cavity, which had gradually grown in size and was interfering with his ability to speak and eat normally. The patient reported that the left mandibular second premolar tooth had been extracted 3 months earlier, but the area had been slow to heal. P/e: large, exophytic, 5x5 cm lobulated mass in the left mandibular vestibular aspect, moderately tender to palpation, and extending from the first premolar area to the retromolar trigone and sublingual regions an incisional biopsy was performed, and histologic examination showed a submucosal mass under a focally ulcerated mucosa, with diffuse infiltration of neoplastic large plasmablastic cells intense immunostaining for cd79a, CD138, and cytoplasmic restricted k-light chains, as well as negativity for l-light chains, CD45, CD20, and other nonlymphoid markers, was also seen. These findings strongly suggested an initial pathologic diagnosis of plasmablastic plasmacytoma versus myeloma.
Remission Characteristics
Patient was planned for radiotherapy. 2 months after his first visit, he was in complete remission without any treatment and before starting radiotherapy